The COVID-19 pandemic drove blood plasma donations down 20% in 2020 – and they declined even further in 2021. Plasma – the yellowish liquid that makes up about 55% of our blood – is a major component in creating lifesaving therapies for burn injury survivors, people who are immune-compromised, people with hemophilia and certain cancer patients. In fact, more than 125,000 Americans rely on therapies made from plasma every day. Take Oliver. As a toddler, Oliver developed a high fever, a swollen tongue, and a rash over his entire body. His father rushed him to the emergency room where they learned he had Kawasaki Disease – a rare condition that involves swelling of blood vessels throughout the body. He received a plasma-derived medication and recovered, but the effects of the disease would later develop into a heart condition that he still lives with today.